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Dissecting the Role of Epithelial Mesenchymal Transition and 1,25(OH)2D3 Activity in EGFR-Mutant Tyrosine Kinase Inhibitor-Resistant Lung Cancer
(State University of New York at Buffalo, 2019)
The body of work presented here describes three in vitro models of EGFR-mutant TKI-resistant NSCLC derived from EGFR TKI-sensitive cell lines in our laboratory. Two cell lines, H1975-OR and SH416-ER, underwent EMT. H1975-OR ...
Representing 9/11: Intermediality, Plurality and Temporality
(State University of New York at Buffalo, 2018)
The September 11 attacks have been often referred to as an unprecedented historical event defining the twenty-first century. Live broadcasts of the event in real time have rendered 9/11 an unprecedented visual disaster ...
Voices of Poverty: Narratives of Homeless and Slum Dwelling Women of India
(State University of New York at Buffalo, 2018)
This main objective of this study was intended to explore the “lived experiences” of the two sections of women who live in poverty in Patna, and in neighboring cities of Bihar in India. According to Besly et.al(2007) in ...
3D Freeze Nano Printing for Multiscale, Multifunctional Porous Materials
(State University of New York at Buffalo, 2018)
Hierarchical porous structures are ubiquitously around us (e.g., bamboo, wood, bone, bird wings). They exhibit many exceptional properties such as light weight, large surface area, and multi-functionality. It would be ...
Fostering Students' Content Knowledge and Argumentation Skills in an Interactive Classroom Discourse with Technology-Enhanced Active Learning Instruction
(State University of New York at Buffalo, 2018)
The purpose of this study was to examine how an engineering classroom community appropriates active learning discourse over a semester that promoted student content knowledge and scientific argumentation. It also assessed ...
The Influence of Genomic Organization on the Diversity of Angiosperms
(State University of New York at Buffalo, 2018)
The origin and rapid diversification of flowering plants has captured the interest of scientists across fields of study including molecular phylogenetics, evolutionary and developmental genetics, morphology, paleobotany, ...
Development of free energy methods to study wetting behavior with molecular dynamics
(State University of New York at Buffalo, 2018)
This dissertation focuses on developing molecular simulation methods to understand the wetting behavior of fluids. Within our group, we have developed an interface potential based approach for determining the interfacial ...
Interfacial Properties of Carbon Dioxide–Water–Silica from Expanded Ensemble Monte Carlo Simulations
(State University of New York at Buffalo, 2018)
This dissertation demonstrates the use of expanded ensemble Monte Carlo simulations to compute the bulk phase coexistence conditions of CO2–H2O mixtures and the interfacial properties of these mixtures over model silica ...
Investigation of Inter-Individual Variability in Monoclonal Antibody Disposition
(State University of New York at Buffalo, 2018)
Substantial inter-individual variability (IIV) in monoclonal antibody (mAb) pharmacokinetics has been reported in the clinic. The sources of variability are not well understood and often not explored. Very few preclinical ...
Feeling American Literature, Reading American Literature: Object Biopolitics in the Traumatized Nation-State
(State University of New York at Buffalo, 2018)
This dissertation outlines strategies for new queer reading practices of literature (grounded in feminist theory, affect theory, and material history) that allow readers to heal, recover from and even empower themselves ...