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Spatio-temporal landscape models for West Nile virus vector population abundance and distribution
(2007)
In response to the rapid spread of West Nile virus throughout North America there has been an increase in the number of mosquito vector surveillance and control programs. However, mosquito surveillance programs are costly ...
Cadmium and mercury suppress cytokine receptor-mediated Jak/STAT activation by inhibiting mitochondrial function and increasing intracellular oxidative stress
(2007)
The Janus kinase (Jak)/signal transducer and activator of transcription (STAT) pathway is an intercellular signal transduction mechanism that acts in many cell types, including neurons, during development and repair after ...
Impact of aging on type I collagen and transforming growth factor-beta1 (TGF-beta1) mRNA expression during muscle degeneration
(2007)
We tested the hypothesis that type I collagen mRNA expression would be lower in injured skeletal muscle from senescent rats compared with young and middle-aged rats, and that this decrease would be associated with a decreased ...
Effects of TNF-alpha on type I collagen and TGF-beta1 mRNA expression in muscle cells
(2007)
The purpose of this study was to determine whether treatment of cultured C 2 C 12 myoblasts and mytotubes with TNF-α over time (24, 48 and 72hrs) would stimulate collagen metabolism either directly or indirectly through a ...
Blood flow measurement from digital angiography
(2007)
Computational fluid dynamic (CFD) simulations are emerging as a promising tool for diagnosis and treatment planning of vascular diseases such as intracranial aneurysms. In addition to the three-dimensional luminal geometry, ...
Vitamin C and collagen IV formation in fibroblasts
(2007)
Collagen IV (Col4) is a major component of vascular basement membranes (BM). Mice expressing mutated Col4 died shortly after birth with cerebral hemorrhage. Mice lacking the ubiquitous vitamin C (Asc) transporter SVCT2 ...
Molecular mechanisms regulating DeltaNp63 expression and function during development and differentiation of mouse skin keratinocytes
(2007)
The skin is a multilayered stratified epithelium providing a protective barrier against dehydration and pathogenic insult. The transcription factor p63 plays an important role in the development of stratified epithelium ...
Molecular mechanism of inhibitor of kappa B kinase (IKK) complex activation by inducible phosphorylation and ubiquitination upon T cell receptor (TCR) stimulation
(2007)
IκB kinase (IKK) complex serves as the master regulator for the activation of NF-κB by various stimuli. It contains two catalytic subunits, IKKα and IKKβ, and a regulatory subunit, IKKγ/NEMO. The activation of IKK complex ...
Microarray and real time-polymerase chain reaction analysis of mammary glands from rats fed conjugated linoleic acid
(2007)
Conjugated linoleic acid (CLA) prevents mammary tumors in rats. The purpose of this study was to test the hypothesis that common pathways are altered by two similarly chemoprotective isomers, 9,11-CLA and 10,12-CLA. ...
Phylogenetics and morphological evolution of Scleractinian corals
(2007)
Scleractinian corals are modular organisms of great ecological and economic importance that may have solitary or colonial growth forms. In spite of the rich fossil record, the evolutionary history of the group is poorly ...