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Anti-cancer activity of novel camptothecin analogues that are insensitive to ABCG2
Analogues of camptothecin (CPT) have been used in the clinic for almost two decades. The first analogue to be approved, topotecan (TPT), is now approved for use in patients with advanced ovarian, cervical, or small cell ...
Streptococcal recognition of sialic acid diversity in the salivary proteome
Saliva facilitates in the preprocessing of food, and contributes to the protection of teeth and oral mucosa. Saliva also helps to maintain an ecological balance in the diverse oral microbiota through the clearance of ...
Assessing PDT response with diffuse optical spectroscopies
Photodynamic therapy (PDT) is used to treat a variety of conditions including cancer. Effective PDT requires three components: a photosensitizer (PS), light of a specific wavelength to activate the PS and oxygen. When all ...