Now showing items 1-10 of 130
Theoretical and experimental investigation of gap junctional conductance and permeability
Gap junctions are intercellular pores providing the primary means for direct exchange between cells, of ions and metabolites up to molecular weights of about 1000. They are essential for normal physiological function and ...
Endothelial cell layer subjected to flow mimicking the apex of an arterial bifurcation
Endothelial cell response to shear stress and shear stress gradients is widely accepted as a mediator of vascular pathology, including intracranial aneurysms. To this point, most in vitro research on endothelial cells ...
Remote sensing and hydrological modeling of burn scars
This study examined the potential usefulness of combining remote sensing data with hydrologic models and mapping tools available from Geographic Information Systems (GIS), to evaluate the effects of wildfire. Four subprojects ...
Correlating in-vivo hemodynamics with vascular responses
The roles of hemodynamics in the natural history of vascular diseases remain unclear due to a lack of understanding of the cellular and molecular responses under various hemodynamic stimuli. In vivo quantitative hemodynamics, ...
A web-based modeling approach for tracking algal blooms in lower Great Lakes
The occurrence of algal blooms in the Great Lakes has been a growing concern over the past few decades, especially for toxic or harmful algal blooms (HABs). For the present work a general circulation model is used to help ...
Development and evaluation of a new high-sensitivity, region-of-interest, x-ray imaging system for neuro-interventional applications
Neurovascular image-guided interventional (IGI) procedures require very high resolution (3 to 10 lp/mm), large dynamic range, and real-time imaging capability for visualization and navigation of endovascular devices during ...
Robust microbial fabrication of plant pharmaceuticals: Complexities and solutions
Abstract not available.
Blood flow measurement from digital angiography
Computational fluid dynamic (CFD) simulations are emerging as a promising tool for diagnosis and treatment planning of vascular diseases such as intracranial aneurysms. In addition to the three-dimensional luminal geometry, ...
High yield anthocyanin biosynthesis in metabolic engineering Escherichia coli
Anthcoyanins, the largest sub-group of flavonoids and a major group of plant pigments, impart the eye-catching hues to most flowers and fruits ranging from pink through red and purple to dark blue. They are widely distributed ...
Recycling acetate for improving flavanones production from Escherichia coli
Acetate is a toxic by-product of glucose metabolism in Escherichia coli. In the present work, endogenous metabolic networks of E. coli were re-designed to improve the autonomous recycling of acetate into acetyl-CoA. In ...