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Regulation of cyclin D1 expression by protein kinase C signaling in the intestinal epithelium
The current addresses the involvement of the Protein Kinase C (PKC) enzyme system in regulation of intestinal homeostasis, with particular emphasis on the role of individual isozymes in control of cyclin D1 accumulation. ...
Zn 2+ activates KCNQ1 and KCNN4 K + channels in T84 human colonic epithelial cells
Oral administration of Zn 2+ has been shown to reduce secretory diarrhea in children, but the mechanisms of action of this anti-secretory agent are unknown. We examined the effects of Zn 2+ on K + channels in secretory ...