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P53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of tandem and interspersed repeats
Inactivation or loss of p53 is associated with increased cell sensitivity to the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-dC). To identify the factors that trigger apoptotic response under these conditions, ...
The effect of group counseling on the quality of life of patients and survivors of pediatric cancer and brain tumors
The purpose of this study was to examine the effect of group counseling on patients and survivors' of pediatric cancer and brain tumors perceptions of quality of life. There were five participants between the ages of 11 ...
Prostate-specific antitumor effects of natural compounds: Isoliquiritigenin and alternol
Prostate cancer is the most commonly diagnosed form of cancer among men in the United States. It is second only to lung cancer as the leading cause of cancer-related deaths in males. The lethality of prostate cancer can ...
Glycan Signature Changes in Stem Cell Differentiation and Cancer
Glycosyltransferase (glycoT) enzymes mediate the transfer of monosaccharide from nucleotide-sugars to carbohydrate, lipid and protein based acceptors leading to formation of glycans. The regulation of the glycan structures ...