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Regulation of hormone responsive cancers by Ca 2+ /calmodulindependent protein kinase kinase 2
Steroid Receptors (SR) are oncogenic drivers of proliferation in hormonally regulated cancers. Immunohistochemistry (IHC) studies have shown high expression levels of Ca2+/calmodulin-dependent kinase kinase 2 (CaMKK2), an ...
The role of CaMKK2 in prostate cancer progression
The androgen receptor (AR) plays a critical role in prostate cancer (PC) progression; however, the molecular mechanisms by which the AR regulates cell proliferation in androgen-dependent and castration-resistant PC (CRPC) ...