Now showing items 1-2 of 2
Defining mechanisms by which fever-range thermal stress regulates natural killer cell mediated recognition and killing of tumor cells
All circulating cells, including Natural Killer (NK) cells, normally experience temperature gradients as they move through compartments in the body; however inflammation-driven febrile conditions can expose them to elevated ...
Regulation of classical and non-classical major histocompatibility complex class I molecules
Lysis of tumor cells by cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells is mediated by the ability of these cells to recognize classical, non-classical and MHC class I related molecules. My work has focused ...