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Living my family's story: Caring for and identifying the lived experience within the context of high risk for hereditary breast cancer
Significance and background . In the past decade, advances in genetic science have given rise to an influx of research and information regarding hereditary risk for breast cancer. This genetic information allows clinicians ...
Pregnancy-related characteristics, genetic variation in estrogen-metabolizing enzymes, and maternal risk of breast cancer
Considerable evidence has accrued from in vitro , clinical, and epidemiologic studies indicating that cumulative lifetime exposure to elevated levels of circulating ovarian hormones, including estrogens and progesterone, ...
Trans-organ and Intra-organ Cancer Susceptibility
Risk of sporadic cancer varies greatly in the population and is influenced by many cancer susceptibility genes collectively. In spite of the large number of cancer susceptibility loci detected in humans or in animal models ...