Now showing items 1-6 of 6
Invasive ductal carcinoma breast cancer with and without a ductal carcinoma in situ component; implications for prevention, prognosis and treatment
Cancer of the breast is a heterogeneous disease, with each tumor having its own history of development. The classical model of breast cancer development describes the steps of tumor progression, starting with the transformation ...
The role of family history and risk of breast cancer aggressiveness in African American and European American women
INTRODUCTION: European-American (EA) women, overall, have higher breast cancer incidence than African-American (AA) women. However, AA women are more likely to be diagnosed at a younger age and to have more aggressive ...
The effect of alcohol exposure during post-lactational involution on mouse mammary tumorigenesis
Breast cancer susceptibility is influenced by dynamic stromal remodeling of the mammary tissue during its various stages of development, such as puberty, pregnancy, lactation, and post-lactational involution. Epidemiological ...
DNA Methylation, Physical Activity and Breast Cancer: The Western New York Exposures and Breast Cancer (WEB) Study
Objective: Global and gene-specific DNA methylation play an important role in breast carcinogenesis. However, the influence of lifestyle factors on DNA methylation is unknown. We examined the association between lifetime ...
Effects of pulsed ethanol consumption on mammary tumorigenesis in non-parous mice
Ethanol has been implicated as the only dietary factor that increases the risk of breast cancer in women. It is not known whether the effects of ethanol exposure are the same throughout the lifetime, or if ethanol exerts ...
Dietary lignan intake and androgen receptor expression in breast tumors
Emerging research has identified the androgen receptor (AR) as a prognostic factor in breast tumors. Lignans, a phytoestrogen commonly found in the Western diet, have been linked to a decreased breast cancer risk in ...