Now showing items 1-10 of 40
Blood flow measurement from digital angiography
Computational fluid dynamic (CFD) simulations are emerging as a promising tool for diagnosis and treatment planning of vascular diseases such as intracranial aneurysms. In addition to the three-dimensional luminal geometry, ...
Development and evaluation of a new high-sensitivity, region-of-interest, x-ray imaging system for neuro-interventional applications
Neurovascular image-guided interventional (IGI) procedures require very high resolution (3 to 10 lp/mm), large dynamic range, and real-time imaging capability for visualization and navigation of endovascular devices during ...
Robust microbial fabrication of plant pharmaceuticals: Complexities and solutions
Abstract not available.
Micromachined polymeric scaffold with neuron factor gradient for guided spiral ganglion neuron growth
Over 50 million people suffer from acquired hearing loss due to permanent damage to hair cells currently treatable by only cochlear implants. The damaged hair cell in turn causes the demise of spiral ganglion neuron, ...
High yields of natural products in recombinant microorganisms using regulatory factors
Control of genetic expression, which is traditionally considered as protein's job, can also be achieved by small mRNA sequences located in 5'-UTR of any gene widely recognized as 'riboswitches'. These riboswitches control ...
Theoretical and experimental investigation of gap junctional conductance and permeability
Gap junctions are intercellular pores providing the primary means for direct exchange between cells, of ions and metabolites up to molecular weights of about 1000. They are essential for normal physiological function and ...
Approaches to clustering gene expression time course data
Conventional techniques to cluster gene expression time course data have either ignored the time aspect, by treating time points as independent, or have used parametric models where the model complexity has to be fixed ...
Functional module identification and function prediction from protein interaction networks
Since the completion of sequencing human genome, uncovering the principles of interactions and the functional roles of proteins has been in the spotlight in this post-genomic era. The interactions between proteins provide ...
Metabolic engineering of Escherichia coli and Saccharomyces cerevisiae to mutasynthesize natural phenylpropanoids and novel analogs
The current dissertation investigated the biosynthesis of natural and unnatural flavonoids using Escherichia coli and Saccharomyces cerevisiae. Flavonoids are a diverse group of secondary metabolites found ubiquitously in ...
Recycling acetate for improving flavanones production from Escherichia coli
Acetate is a toxic by-product of glucose metabolism in Escherichia coli. In the present work, endogenous metabolic networks of E. coli were re-designed to improve the autonomous recycling of acetate into acetyl-CoA. In ...