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Irradiance: A parameter determining oxygenation during topical photodynamic therapy (PDT)
(2010)
PDT requires photosensitizer (PS), light and oxygen to generate the cytotoxic agent singlet oxygen ( 1 O 2 ). The topically applied pro-PSs aminolevulinic acid (ALA) and methyl 5-aminolevulinate (MAL), which lead to the ...