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The role of CaMKK2 in prostate cancer progression
The androgen receptor (AR) plays a critical role in prostate cancer (PC) progression; however, the molecular mechanisms by which the AR regulates cell proliferation in androgen-dependent and castration-resistant PC (CRPC) ...
Analysis of androgen receptor signaling and DNA methylation dynamics in prostate biology
DNA methylation is an epigenetic modification that contributes to stable gene silencing by interfering with the ability of transcriptional regulators to bind to DNA and, when found at high density, by recruiting ...
The altered function and expression if iPLA2-beta in prostate tumor cells
Growth, development, and function of the prostate gland are regulated through the androgen receptor (AR), and prostate cancer is associated with aberrant regulation of the AR. Three isoforms of a recently discovered calcium ...