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Role of Endogenous Melatonin on the Regulation of Circadian Reentrainment, and Melatonin Receptors and Clock Gene Expression in C57BL/6J Mice
Melatonin is synthesized primarily in the pineal gland via the enzymes arylalkylamine N-acetyltransferase (AA-NAT) and hydroxyl-indole O-methyltransferase (HIOMT). The synthesis and release follows a circadian rhythm with ...
Circadian modulation of reward via the MT1 and MT 2 melatonin receptors
The goal of our research was to investigate the underlying connections between the reward and circadian systems. Diurnal variation in reinforcement-related process has been described in models of place preference, ...