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Role of Endogenous Melatonin on the Regulation of Circadian Reentrainment, and Melatonin Receptors and Clock Gene Expression in C57BL/6J Mice
Melatonin is synthesized primarily in the pineal gland via the enzymes arylalkylamine N-acetyltransferase (AA-NAT) and hydroxyl-indole O-methyltransferase (HIOMT). The synthesis and release follows a circadian rhythm with ...
Melatonin receptor-mediated modulation of multiple behavioral rhythms in mice
High affinity melatonin receptors are expressed in different regions of the central nervous system and modulate processes that can modify behaviors. The goal of our research was to investigate the role of endogenous melatonin ...