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Identification of sufficient basolateral-targeting sequence in N-terminus of human sodium-dependent vitamin C transporter 2
Human sodium-dependent vitamin C transporters, hSVCT1 and hSVCT2 are responsible for the uptake of L-ascorbic acid in the body. Sharing 66% amino acid sequence homology, these two transporters are functionally localized ...
Heterologous NH2-terminal basolateral targeting sequence for multipass transmembrane protein in epithelial cells
Sodium-dependent vitamin C transporters (SVCTs), SVCT1 and SVCT2, share 66% identical amino acid sequence but differentially localize to the apical and basolateral surface in MDCK cells, respectively. The N-terminal sequence ...