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Investigating feasibility of repetitive transcranial magnetic stimulation targeting upper limb spasticity- a case study
(State University of New York at Buffalo, 2019)
Spasticity is one of the major disability that affects an individual and his caregivers’ lives in many ways. Spasticity is usually caused due to stroke, traumatic brain injury, multiple sclerosis to name a few. It occurs ...
The effects of immune factor, TNFα, on human fetal neural development and schizophrenia in a cerebral organoid model
(State University of New York at Buffalo, 2019)
Schizophrenia (SZ) is a psychiatric disease, which affects approximately one percent of the global population. Schizophrenia is a neurodevelopmental disorder, which affects in utero brain development within the first ...
Characterization of novel alpha2/alpha3 subtype-selective GABAA receptor positive allosteric modulators
(State University of New York at Buffalo, 2019)
Millions of individuals endure persistent pain. In the United States alone, about 30% of the population is estimated to suffer from chronic pain. In addition to the physical and emotional burden that chronic pain imparts, ...
Aberrant immune states of the inner ear resultant of aging and lower level noise
(State University of New York at Buffalo, 2018)
Cochlear immunity is an important process for cochlear homeostasis and diseases. Over the past twenty years, numerous researchers have investigated cochlear immunity as it pertains to inner ear stresses. However, the vast ...
Affective Neurothriller: A Gendered Approach
(State University of New York at Buffalo, 2018)
The purpose of this thesis is to situate what Patricia Pisters calls the contemporary neurothriller through a gendered lens. The emergent field of neurofilmology and neuroaesthetics set the stage for Patricia Pisters’ ...
Lipid Biomarkers in Multiple Sclerosis Pathogenesis
(State University of New York at Buffalo, 2018)
The purpose of the work presented in this dissertation was to investigate the role of cholesterol metabolism in the pathogenesis of multiple sclerosis (MS). Serum lipid profile measures have previously been shown to be ...
SYNAPTIC TUNING FOR ENHANCED DYNAMIC SENSITIVITY AT PHOTORECEPTOR TERMINALS
(State University of New York at Buffalo, 2019)
Studies of the aspartate-isolated a-wave response from the all-rod retina of the skate, Raja erinacea, have demonstrated that its incremental sensitivity remains Weber-Fechner-like as the intensity of steady background ...
Magnetothermal Neuromodulation
(State University of New York at Buffalo, 2019)
To understand the phenotypical and aberrant aspects of brain functions, circuital elements within the brain need to be perturbed and the effects correlated. However, the fast dynamics and the complex heterogeneity of neural ...
Dynamic Cerebral Blood Flow Velocity Assessment during Head Down Tilt in Sports-Related Concussions
(State University of New York at Buffalo, 2019)
AbstractIntroduction: Sport-related concussions affect between 1.6 and 3.8 million people in the United States per year (Langlois et al., 2006). Approximately 5% to 10% of children and adolescents will experience a ...
Activity-dependent changes at the auditory nerve synapse
(State University of New York at Buffalo, 2018)
Information transfer at chemical synapses occurs when vesicles fuse and release neurotransmitter. This process is tightly regulated and must maintain stable function when faced with different levels of activity. Three main ...