Now showing items 91-95 of 95
Chemical and Biological Attenuation Methods for Bacterial Mediated Gene Delivery
The development of nonviral vectors for safe and effective gene delivery system is acquiring significant consideration at the present time. Ideally a nonviral vector must overcome the barrier of extracellular milieu, ...
The transcirptomic and methylomic changes caused by subtoxic doses of 5-Azacytidine and 5-Aza-2'-deoxycitide
5-Aza-2'-deoxycytidine (5-Aza-CdR) and 5-Azacytydine (5-Aza-CR) are used to treat myelodysplastic syndrome (MDS) in the clinic. Additionally, a number of clinical trials have shown the efficacy of the drugs in solid tumors. ...
Development of small molecule inhibitors targeting the C-terminal scaffold of focal adhesion kinase
FAK functions as both, a critical signaling kinase and a scaffolding protein to collectively mediate cell proliferation, survival, adhesion, migration, invasion, and angiogenesis. The scaffolding function of FAK is mediated ...
Effects of Anxiety Symptoms on the Masticatory Muscle Activity of Subjects with TMD-Pain Diagnoses
Temporomandibular disorders (TMD) is a collective term embracing a number of clinical problems that involve the masticatory muscles, the temporomandibular joint and associated structures, or both The prime manifestation ...
Selected Topics on Statistical Methods for Three and Multiple Class Diagnostic Studies
Many disease processes such as Alzheimer'sDisease have three ordinal disease classes, i.e. the non-diseased stage, the early diseased stage and the fully diseased stage. Since the early diseased stage is likely the best ...