Now showing items 101-105 of 105
Cognitive Adaptation for Human Computer Interaction
Recognition of user's mental engagement is imperative to the success of Human Machine Interaction (HMI). By conducting a series of human experiments, we obtain implicit information about the cognitive and affective state ...
Effects of glucose and flow on reactive oxygen species in brain artery endothelial cells
Endothelial cells play a vital role in the normal physiology of the vasculature. The cerebrovascular region is highly populated by endothelial cells with distinct morphology and functions. However, endothelial cells are ...
A novel approach to using combinatorial AAV to knockdown the D2 autoreceptor from specific pathways
Mesolimbic dopamine neurotransmission is largely implicated in the motivation to abuse drugs. A number of studies have indicated that dopamine D2 receptor expression and function are altered in drug addicts. However, ...
Estrogen receptor (ER) alpha-mediated regulation of the p53-targets MDM4, MDM2 and NOXA in human breast cancer
In this dissertation, I present the results of my investigation of the ability of ERα/ESR1 to regulate the p53-regulated proteins MDM2, MDM4 and NOXA/PMAIP1 in human breast cancer, and I discuss these findings in the context ...
Role of FUT7 during leukocyte adhesion and extravasation
Leukocyte adhesion and transmigration from blood flow on the endothelial cells is an important cascade of processes during inflammation. The initial leukocyte capturing is mediated by binding of P-selectin expressed on the ...