Now showing items 121-122 of 122
Breast epithelial morphogenesis: The role of annexins and primary cilia
Models of three dimensional (3D) mammary acinar morphogenesis are extensively used to study oncogenic transformation of breast epithelial cells. Using these models, factors and mechanisms that lead to aberrant 3D acinar ...
Optimizing polymyxin antibiotics using combination therapy and mechanism-based models
The emergence of multidrug-resistant (MDR) Gram-negative 'superbugs' coupled with a rapid decline in the development of new antibiotics has led to a serious, global health crisis. Polymyxin antibiotics, which include ...