Now showing items 161-164 of 164
Functional characterization of trypanosoma mRNA capping enzymes and archaeal RNA ligase
The dissertation consists of three chapters. In chapter 1, I present the characterization of the Trypanosoma brucei mRNA capping enzyme apparatus. The 5’ end of kinetoplastid mRNA possesses a hypermethylated cap 4 structure, ...
A cell culture model of HDL metabolism in human ovarian Granulosa cell line KGN
Background . High density lipoprotein (HDL) is the sole lipoprotein found in mammalian ovarian follicular fluid (FF) and there is evidence that HDL cholesterol levels and HDL particle remodeling within the ovarian follicle ...
A guidance system for optical patient alignment during breast radiotherapy
Breast radiotherapy, particularly IMRT, involves large dose gradients and difficult patient positioning problems. A critical requirement for successful treatment is accurate reproduction of the patient's position assumed ...
Keratinocyte as a model system for transcriptional control of epithelial homeostasis and carcinogenic transformation
Keratinocytes are specialized epithelial cells making up most of the stratified squamous epithelia of the mammalian epidermis and oral mucosa. In these epithelial tissues, the keratinocytes are arranged such that the ...