Now showing items 251-253 of 253
Involvement of the thalamus in the progression of multiple sclerosis: A study of the musculus counterpart in Theiler's murine encephalomyelitis virus infection
Multiple sclerosis (MS) has long been known as a disease of demyelination involving the white matter (WM), but atrophy of the gray matter (GM) is also seen in MS, and is associated with clinical symptoms of the disease. ...
Mixed Effects Modeling of Recurrent Events: A Generalized Frailty Model Approach
In this dissertation, I propose an extension of frailty modeling to analysis recurrent events data. A class of models based on nonlinear mixed effects modeling is proposed that takes into consideration additional sources ...
Effect of defucosylation on humanized JAA-F11 antibody against TF-antigen and comparison of cytotoxicity with fucosylated counterparts
JAA-F11 is a mouse monoclonal antibody specific to Thomsen Friedenreich Antigen, which is a carbohydrate antigen expressed on several types of carcinomas and serves as a novel target for development. Humanization of the ...