Now showing items 251-253 of 253
The roles of metabotropic GABA receptor in retina circuitry
GABAergic amacrine cell feedback to bipolar cells has been described, activating both GABA A and GABA C receptors. We explored whether metabotropic GABA B receptors also participate in this feedback pathway. Two approaches ...
Pharmacokinetics and lymphatic absorption of the protein VEGF-C156S
Lymphedema is a disorder of the lymphatic vascular system characterized by lymphatic insufficiency that leads to blockade of lymph flow and swelling of the extremities. VEGF-C156S is a recombinant mutant form of human ...
Heterologous NH2-terminal basolateral targeting sequence for multipass transmembrane protein in epithelial cells
Sodium-dependent vitamin C transporters (SVCTs), SVCT1 and SVCT2, share 66% identical amino acid sequence but differentially localize to the apical and basolateral surface in MDCK cells, respectively. The N-terminal sequence ...