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Now showing items 21-30 of 32
Tumor imaging and photodynamic therapy (PDT) using versatile chlorin near infrared fluorophore (NIRF) conjugates
(2013)
Near-infrared (NIR) organic dyes have become important for many biomedical applications, including in vivo optical imaging. Conjugation of NIR fluorescent dyes to photosensitizing molecules (photosensitizers) holds strong ...
Understanding of human immunodeificiency virus-1 entry inhibition and co-pathogenesis of human immunodeificiency virus-1 and Cryptococcus neoformans in variably polarized macrophages
(2013)
HIV/AIDS is now seen as a chronic disease in developed countries, whereas it still causes a great burden in developing countries. There have been global efforts to develop treatments and chemopreventive agents to prevent ...
Military load carriage during prolonged marches on lower extremity mechanics: Influence of gender
(2013)
INTRODUCTION: Stress fractures are the most commonly reported orthopedic injury among military recruits. Whereas females are 2-3 times more likely to incur stress fractures when engaged in athletic activity compared to ...
Gender and pubertal differences in cognitive responses to caffeine
(2013)
Background: Caffeine has been found to improve cognitive performance in adults, but few studies have looked at children. Purpose: The purpose of this study was to test the hypothesis that caffeine improves cognitive ...
The characterization and removal of surgical smoke produced by electrosurgical and laser devices
(2013)
The main focus of this study was to characterize the physical and chemical make-up of ESU and diode laser surgical smoke produced from different tissue types, and the efficacy of the Turbo smoke extractor in reducing smoke ...
Insights into Colonization, Transformation and the Transition to Disease of Streptococcus pneumoniae And Possible Targets for Therapeutic Interventions
(2013)
The studies described in this thesis explore the physiology of upper respiratory tract colonization by S. pneumoniae and S. pyogenes. We have shown that colonization is associated with biofilm formation and examined the ...
Respiratory Muscle Training Improves Exercise Endurance at Altitude
(2013)
People have been traveling to high altitude for centuries where they are faced with adverse environmental conditions. As one ascends to elevation, the barometric pressure is reduced and the air gets thinner. These changes ...
A novel type of non-PK related genes controls susceptibility to the toxic effects of irinotecan
(2013)
Adverse drug reactions (ADRs) are a major obstacle in cancer chemotherapy. In spite of the advances in the development of anti-cancer drugs, ADRs compromise their potential benefits in many patients by imposing reduction ...
Identification and characterization of novel focal adhesion kinase substrates: Programmed cell death 6
(2013)
Focal Adhesion Kinase (FAK) is a major signaling molecule which functions downstream of integrins or in conjunction with mitogenic signaling pathways. FAK is overexpressed and/or activated in many types of human tumors, ...
Overcoming Obstacles to Naïve T Lymphocyte Trafficking in Anti-Tumor Immunity
(2013)
Tumor-draining lymph nodes (TdLN) are the primary sites of generation of anti-tumor immunity, and thus, have emerged as key contributors to the efficacy of cancer treatment during chemotherapy, radiation, surgery, and ...