Now showing items 21-25 of 25
Tumor imaging and photodynamic therapy (PDT) using versatile chlorin near infrared fluorophore (NIRF) conjugates
Near-infrared (NIR) organic dyes have become important for many biomedical applications, including in vivo optical imaging. Conjugation of NIR fluorescent dyes to photosensitizing molecules (photosensitizers) holds strong ...
X-ray region of interest imaging system for rapid-sequence angiography and fluoroscopy: The micro-angiographic fluoroscope
Neuro-endovascular interventional diagnosis and treatment require high resolution x-ray imaging guidance of fluoroscopy and angiography. Our group has developed a small field of view, 5 frames per second, high-resolution ...
Assessing PDT response with diffuse optical spectroscopies
Photodynamic therapy (PDT) is used to treat a variety of conditions including cancer. Effective PDT requires three components: a photosensitizer (PS), light of a specific wavelength to activate the PS and oxygen. When all ...
Analysis of the biosynthesis and function of a serotype B glycoform of Moraxella catarrhalis lipooligosaccharides
Moraxella catarrhalis is an important human pathogen and a major cause of otitis media in children and respiratory infection in adults with chronic obstructive pulmonary disease (COPD). Few virulence factors have been ...
Optimization of tumor-imaging and therapeutic potential of near-infrared multifunctional agents, and targeted polyacrylamide theranostic nanoplatforms
The goal of this work was to modify the structural parameters of porphyrin-based agents to optimize their imaging and/or therapeutic potential. In order to achieve our goal, certain chlorins and bacteriochlorins were ...