Now showing items 351-356 of 356
Assessing the prognostic utility of TCGA breast cancer dataset
Besides skin cancer, breast cancer is the most common type of malignancy among women in the United States and the second most common cause of cancer death in this population group. As with many other types of cancer, breast ...
Relationship between Obesity and MRI Conventional and non-conventional MRI Outcomes in Healthy Adults Without Neurological Disease
Introduction . There is evidence that obesity contributes to lesion formation, axonal damage and brain volume loss. Objective . The effect of obesity on brain damage was examined assessing microstructural tissue damage ...
Osseoconductive interactive effect of two nanocrystalline calcium sulphate products supplemented with titanium meshes on human osteoblast biological behavior
Objective: In cases of advanced bone loss, nCS graft cannot be solely used as a filler material due to, the graft fast biodegradation rate and the insufficient mechanical strength. The study goal was to assess HOB’s viability ...
Redirecting cancer kinase signaling: A novel rewiring of Bcr/Abl and PKC Beta II
Mutations in cancer very frequently cause aberrant signal transduction. This dysfunctional signaling blocks apoptotic and differentiation pathways, activates proliferative and survival pathways, and plays a central role ...
Understanding the Impact of Adrenergic Stress on the Therapeutic Response of Murine Cancer Models
Laboratory mice are indispensable tools used in cancer research to model and study multiple aspects of tumor biology. In particular, the development of new therapies for the treatment of cancer has relied heavily on murine ...
Influenza and secondary bacterial pneumonia: Modulation of the host anti-viral immune response and the interferon paradox
In 1918 the influenza virus (flu), in terms of total fatalities, was responsible for the worst pandemic the world has ever seen. The major cause of death is now attributed to secondary bacterial pneumonia. Flu infection ...