Now showing items 31-40 of 918
Quantum mechanical effects in gravitational collapse
In this thesis we investigate quantum mechanical effects to various aspects of gravitational collapse. These quantum mechanical effects are implemented in the context of the Functional Schrödinger formalism. The Functional ...
Analysis and fate of pharmaceuticals and quantum dots as emerging contaminants in the aquatic environment
Environmental contaminants such as pharmaceutical residues and nanomaterials are an ecological concern as they pose potential undesirable effects on the biota. Pharmaceutical compounds and their metabolites are detected ...
Gonadotropin stimulated apolipoprotein A-IV gene expression in human ovarian granulosa cells in vitro
Background. There is increasing evidence that high density lipoprotein (HDL) metabolism is important to mammalian female fertility. HDL is the sole lipoprotein in human ovarian follicular fluid (FF) and FF-HDL levels have ...
Synthesis and characterization of sol-gel-derived xerogel films with antifouling/foul release properties and the preparation, immobilization, and evaluation of a sequestered selenoxide catalyst for brominations with hydrogen peroxide and sodium bromide in an aqueous environment
Xerogel films with uniform surface topogrophy, as determined by scanning electron microscopy, atomic force microscopy (AFM), and time-of-flight secondary ion mass spectrometry, were prepared from aminopropylsilyl-, ...
Two classes of virtually fibered Montesinos links of type SL2
We find two new infinite families of virtually fibered Montesinos links of type [special characters omitted].
Development of computational and chemical tools to improve methods for targeting RNA with small molecules
The ubiquitous role of RNA in living systems is becoming more and more apparent each year. Historically RNA was treated as a passive carrier of genetic information from its more stable chemical brother DNA, to a more ...
Extensions for the use of the epsilon -skew -normal distribution for modeling data
A common assumption for a number of statistical applications involving continuous data, is to assume the data are normally distributed. In the event the normality assumption is in question Box-Cox transformations to the ...
I:- Design, synthesis and study of nucleotide prodrugs. II:- Synthesis of 5-fluoro-6-[(2-aminoimidazol-1-yl)methyl]uracil (AIFU) and study of its mechanism of action as a thymidine phosphorylase inhibitor. III:- Design and synthesis of novel nucleotide analogs as alternative substrates for studying the mechanism of the thymidylate synthase-catalyzed reaction.
CHAPTER I: Design, synthesis and study of nucleotide prodrugs. In the past, several phosphate masking strategies have been developed with the objective of delivering nucleoside monophosphates into cells for improving the ...
In vitro imaging using stable, water dispersible luminescent silicon quantum dots capped with various cellular targeting agents
This thesis presents research on the synthesis, functionalization, and biological applications of silicon nanocrystals, also called silicon quantum dots (Si QDs). Over the past 20 years, semiconductor nanocrystals (also ...
Strategies for absolute configuration assignments of organic molecules aided by first-principles computations
The absolute configuration assignments of organic molecules by the comparison of experiment with computed chiroptical response are a useful tool in chemistry. However, such assignments are challenging to perform if the ...