Now showing items 31-40 of 328
An emulsion of dodecafluoropentane (DDFPe) sustained oxygen delivery in spontaneously breathing swine after hemorrhagic shock
Twelve spontaneously air breathing anesthetized male swine had a 48.7 ± 0.55 (s.e.) % reduction of their circulating blood volume through a controlled hemorrhage. The large decrease in the swines' circulating blood volume ...
The effects of Quaternary glacial cycles on the evolution of Holarctic Daphnia
Abstract not available.
Insights into eyespots: Gene expression and function in the development of butterfly wing color patterns
The eyespot color patterns of the butterfly, Bicyclus anynana , have become an important system in which to examine the developmental basis of evolutionary novelties. Many candidate genes have been screened, based upon ...
Studies of structure, hydration and dynamics of biological macromolecules by use of NMR spectroscopy
Nuclear magnetic resonance (NMR) has emerged as a powerful tool for studying biological macromolecules in aqueous solution. This dissertation describes the efforts to study the structure, hydration and dynamics of biological ...
The role of RIP ubiquitination in the TNFalpha signaling pathway
Stimulation of cells by TNFα triggers recruitment of various signaling molecules, including RIP, to the TNFα receptor 1 complex, which leads to activation of NF-κB. Previous studies indicate that RIP plays an essential ...
Effects of conjugated linoleic acid on stromal cells in the mammary gland
Stromal cells represent a novel target for chemopreventively modifying the breast microenvironment. The purpose of these studies was to test the hypothesis that conjugated linoleic acid (CLA) acts chemoprotectively against ...
The association between acute myeloid leukemia and body mass index in an adult population
Obesity has been associated with a number of chronic medical conditions. Data from a limited number of studies have suggested that BMI (body mass index) may be implicated in the development of acute myeloid leukemia (AML) ...
The role of nuclear AKT in cell survival
The overall objective of this dissertation is to investigate the mechanism of AKT nuclear translocation and the potential role of nuclear AKT in cell survival. We demonstrated that both endogenous and transiently transfected ...
Vitamin C and collagen IV formation in fibroblasts
Collagen IV (Col4) is a major component of vascular basement membranes (BM). Mice expressing mutated Col4 died shortly after birth with cerebral hemorrhage. Mice lacking the ubiquitous vitamin C (Asc) transporter SVCT2 ...
Reinforcing value of interval and continuous exercise above and below the ventilatory threshold
Purpose. During play children engage in intermittent bouts of activity less than 15 seconds in duration, much like interval training. These short bouts comprise 95% of their total physical activity. Despite this observed ...