Now showing items 51-55 of 55
Structural elucidation of cyclooxygenase enzymes provides insight into the specific stereochemistry of the cyclooxygenase reaction mechanism along with the formation of 15R cyclooxygenase products
Cyclooxygenase (COX) enzymes are heme containing enzymes that catalyze the conversion of Arachidonic (AA) to prostaglandin H 2 (PGH 2 ) during the committed step in prostanoid biosynthesis. This consists of two sequential ...
Topological excitations and fluctuations in superconducting nanostripes
Described in this dissertation is the investigation of competition between one- and two-dimensional topological excitations, phase slips and vortices, in the formation of resistive states in quasi-two-dimensional superconductors ...
Application of carbon-hydrogen activation/Cope rearrangement methodology towards the total syntheses of Pseudopterosin, Elisabethatriene and Vinigrol
C-H functionalization by means of rhodium carbenoid induced C-H insertion provides new strategies for the construction of C-C bonds. The success of this methodology is attributed to the combination of the donor/acceptor- ...
Lanthanide(III)-macrocyclic complexes as catalysts for RNA cleavage and para-cest agents
Five mononuclear europium(III) complexes of 1,4,7-tris(carbamoylmethyl)- 1,4,7,10-tetrazacyclododecane (1) , 1,4,7-tris[(N-ethyl)carbamoylmethyl]-1,4,7,10- tetraazacyclododecane (2) , 1,4,7-tris[(N-N-diethyl)carbamoylmet ...
Systems based studies on the regulation of glycosyltransferase enzyme activities in human leukocytes: Enzymology measurement, metabolic inhibition and mathematical modeling
The emerging field of Glycomics requires the collection and integration of glycosyltransferase data at the gene and enzyme level for the purpose of hypothesis generation. We systematically examined the relationship between ...