Now showing items 61-64 of 64
Comorbidity of chronic pain and depression: The hippocampus as a common denominator
Patients who suffer from chronic pain are often afflicted with depressive illness as well, and vice versa. Antidepressants are common forms of treatment for both chronic pain and depression, but a definitive mechanism of ...
Role of DNA binding in Varicella Zoster IE62 transactivation
The Varicella Zoster Virus (VZV) IE62 protein is the major viral transactivator and is the most extensively studied VZV immediate early (IE) protein due to its importance in viral gene regulation. Little however is known ...
Molecular & environmental regulation of biofilm determinant expression in Aggregatibacter actinomycetemcomitans
The periodontopathogen Aggregatibacter actinomycetemcomitans form biofilms that adhere tenaciously to abiotic surfaces. Fimbriae, lipopolysaccharide (LPS) and extracellular polymeric substance (EPS) contribute to the ...
Irradiance: A parameter determining oxygenation during topical photodynamic therapy (PDT)
PDT requires photosensitizer (PS), light and oxygen to generate the cytotoxic agent singlet oxygen ( 1 O 2 ). The topically applied pro-PSs aminolevulinic acid (ALA) and methyl 5-aminolevulinate (MAL), which lead to the ...