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The genetics of sleep behavior and the association with breast cancer risk and aggressiveness
(2016)
Because breast cancer is such a common cancer and affects a substantial proportion of women, it is important to thoroughly understand the factors that may increase a woman’s risk. Night shift work is one factor that has ...
Effectiveness of dental arch expansion: A preliminary study of two customized fixed lingual orthodontic systems
(2016)
Background: The integration of modern technology has driven the customization of lingual orthodontic appliances. Orthodontic expansion is among the touted advantages of fully customized lingual orthodontic systems. Purpose: ...
Telomeres as targets for persistent organic pollutants: The Anniston community health survey
(2016)
Background: Telomeres are tandem nucleotide repeats on the ends of chromosomes that maintain genomic stability. Telomere length (TL), measured in DNA extracted from peripheral blood, has been posited as a potentially useful ...
The impact of DNA methyltransferase inhibitor treatment on tumor cell recognition by CD8+ T cells and their effector function
(2016)
The azanucleosides, azacitidine (AZ) and decitabine (DA), are FDA approved and have become the standard of care for the treatment of myelodysplastic syndrome (MDS) and low blast count acute myeloid leukemia (AML). About ...
Awareness Of Medication-Related Osteonecrosis Of The Jaw (MRONJ) Among Oncology Dental Patients With Risk Factors For MRONJ
(2016)
Introduction: Medication related osteonecrosis of the jaw (MRONJ) is exposed bone in the maxillofacial region that does not heal within eight weeks after identification by a health professional. Cancer patients taking or ...
The role of data in clinical decision-making: A descriptive study
(2016)
The present descriptive study evaluated 224 short term goals contained within therapy logs completed by pre-professional speech-language pathology students at a university based speech-language and hearing clinic. Recorded ...
Proteomics-Assisted Discovery of Novel Anti-Cancer Agents Targeting The Human Estrogen Receptor Interactome
(2016)
Estrogen mediates various cellular processes including cell proliferation, differentiation, growth and mammary gland function. Estrogen Receptors (ERs) are present in 70% of breast cancers. Consequently, estrogen mediated ...
Synthesis of Novel TCNQ analogous Dyes for Use with Dye Sensitized Solar Cell Chemistry, Specifically With Intended Application Towards Production Of Solar Hydrogen
(2016)
With the looming problem of climate change imposing a significant threat from both a humanitarian and economic view, and the ever increasing demand for more energy in the developing world, a practical source of cheap, ...
Mixed Effects Modeling of Recurrent Events: A Generalized Frailty Model Approach
(2016)
In this dissertation, I propose an extension of frailty modeling to analysis recurrent events data. A class of models based on nonlinear mixed effects modeling is proposed that takes into consideration additional sources ...
Effect of defucosylation on humanized JAA-F11 antibody against TF-antigen and comparison of cytotoxicity with fucosylated counterparts
(2016)
JAA-F11 is a mouse monoclonal antibody specific to Thomsen Friedenreich Antigen, which is a carbohydrate antigen expressed on several types of carcinomas and serves as a novel target for development. Humanization of the ...