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TNF in the hippocampus: Changes in the levels of this cytokine regulate symptoms of chronic pain and depression
An increased level of the cytokine tumor necrosis factor alpha (TNFα) has been shown to be involved in the manifestation of both chronic pain and depression with respect to the hippocampus. Previous studies in this lab ...
Effect of intense noise on neuronal cell production in the adult rat brain
The hippocampus, a major source of neuronal precursor cells and neurogenesis, plays a vital role in memory function, spatial navigation, learning, and mood. There are various factors which enhance or reduce the rate of ...
Comorbidity of chronic pain and depression: The hippocampus as a common denominator
Patients who suffer from chronic pain are often afflicted with depressive illness as well, and vice versa. Antidepressants are common forms of treatment for both chronic pain and depression, but a definitive mechanism of ...