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Biochemical analysis of the role of the conserved hydrophobic cleft on the Escherichia coli beta clamp in DNA replication
The Escherichia coli β processivity clamp interacts with multiple factors involved in DNA replication, repair and damage tolerance. This suggests a role for the clamp in the coordination of these processes. A conserved ...
Determinants of late replication timing in fission yeast telomeres
The process of DNA replication is highly regulated to ensure that DNA integrity is not compromised. Eukaryotic cells have multiple replication origins within their genome to initiate replication and ensure that all DNA is ...