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Examination of the role of DNA methylation changes in prostate cancer using the Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) model
The objectives of this dissertation are (1) to characterize DNA methyltransferase (Dnmt) expression and aberrant DNA methylation throughout TRansgenic Adenocarcinoma of Mouse Prostate (TRAMP) tumor progression; (2) to ...
Cancer/Germline (CG) antigens and epigenetic deregulation in human epithelial ovarian cancer (EOC)
Cancer/Germline (CG) antigen genes have been utilized as immunotherapeutic targets in vaccine-based anti-cancer treatments. Although this approach elicits immune responses and promising outcomes in patients, obstacles such ...