Now showing items 1-5 of 5
Bioanalytical applications of electrospray ionization mass spectrometry for proteome and biomarker analysis
Liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS) has become a valuable tool for proteome and biomarker analysis. The work presented in this dissertation focused on the development MS based methods, ...
Nanoelectrospray mass spectrometry for molecular non-covalent interactions and proteomics
Mass spectrometry has become an indispensable tool in biological analysis. Electrospray ionization is an important tool in the study and characterization of non-covalent molecular complexes because it is a soft ionization ...
The use of mass spectrometry in biomarker discovery and molecule identification
Over the past few years greater emphasis has been placed on biomarker discovery. Of most importance is identifying potential protein biomarkers of disease in biological fluids. Identification of such biomarkers would allow ...
Effects of carboplatin-induced inner hair cell loss on auditory perception in chinchilla
The mammalian inner ear, the cochlea, contains two distinct sensory cell types, inner hair cells and outer hair cells. Previous studies have shown that outer hair cell damage leads to hearing impairments in which threshold ...
The development of mass spectrometric techniques in the analysis of biomarkers and compounds of pharmaceutical and environmental interest
Mass spectrometry has become an invaluable tool to a wide range of biological, chemical, and physical research endeavors. It is routinely used in both the pharmaceutical and biotechnology industries, as well as the ...