Now showing items 1-6 of 6
The cis-trans regulatory circuit mediating RTK/Ras signaling in visceral muscle founder cell specification
Cell fate specification is a fundamental approach for a cell to acquire unique identity from a group of undifferentiated cells during metazoan development, and it requires fine transcriptional regulation of target genes ...
Oxysterol analysis in neurodegenerative diseases and traumatic brain injury
Background: There is increasing evidence that an adverse cholesterol profile is associated with neurodegenerative diseases and CNS injury. Oxysterols are oxygenated metabolites of Cholesterol that may provide the link ...
Imaging-guided preclinical trials of vascular targeting in prostate cancer
Purpose: Prostate cancer is the most common non-cutaneous malignancy in American men and is characterized by dependence on androgens (Testosterone/Dihydrotestosterone) for growth and survival. Although reduction of serum ...
The effect of auditory memory load on intensity resolution in individuals with Parkinson's disease
Purpose: The purpose of the current study was to investigate the effect of auditory memory load on intensity resolution in individuals with Parkinson's disease (PD) as compared to two groups of listeners without PD. Methods: ...
Expression changes of canine transporter targeting-related genes during epithelial cells differentiation determined by microarray analysis and RT-PCR
The establishment and continuous renewal of differentiated apical and basolateral plasma membrane domains with distinct transporters play important roles in maintaining functions of epithelial cells. This process is initiated ...
Emerging Environmental Contaminants and the Metabolic Effects of Exposure Investigated by Mass Spectrometry
Contaminants released into the environment at very low concentrations pose special analytical and toxicological challenges. Low concentrations require long exposures or very sensitive tests to assess the potential toxic ...