Now showing items 1-2 of 2
Targeting EGFR and ErbB2 by small molecule tyrosine kinase inhibitors in human colon cancer
With the understanding of the molecular pathogenesis of colorectal cancer, novel molecular targeted therapies are being developed that may improve treatment of colorectal cancer. The identification of a causal role of ...
Evaluating sources of intrachromosomal instability in sporadic cancer genomes
Genomic instability is one of the hallmarks of tumorigenesis, although it is still disputed if this process acts as a progression facilitator, or is a secondary consequence of malignancy. Intrachromosomal genomic instability ...