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Role of the Escherichia coli beta-clamp, RecA activation and the SOS response in DNA polymerase selection
Error-prone DNA polymerases (pols) are conserved in all three kingdoms of life to promote the potentially mutagenic process of translesion DNA synthesis (TLS) following DNA damage. Due to their reduced fidelity, organisms ...
RecA and repressor: Working together to save phage
The CI repressor protein of bacteriophage 434 is a transcriptional regulator of the life cycle of bacteriophage 434. 434 repressor directs transcription of its own gene while repressing transcription of genes that are ...