Now showing items 1-10 of 25
Development of Nano-Liposomal Formulations of Epidermal Growth Factor Receptor Inhibitors and their Pharmacological Interactions on Drug-Sensitive and Drug-Resistant Cancer Cell Lines
A rapidly expanding understanding of molecular derangements in cancer cell function has led to the development of selective, targeted chemotherapeutic agents. Growth factor signal transduction networks are frequently ...
Fibroblast modulation of T lymphocyte activation
Fibroblasts are a dominant cell type amongst the mixed population of tumor, stromal, and inflammatory cells found in the microenvironment of most human solid tumors. The possibility that fibroblasts have the capacity to ...
Periodontal disease and cancer: Chronic inflammation - the oral-systemic link
Abstract removed at author's request.
Both FLT3-ITd and NPM1 mutations are associated with decreased MLLT3 mRNA expression in acute myeloid leukemia
BACKGROUND: Acute myeloid leukemia (AML) is a molecularly heterogeneous disease characterized by the accumulation of acquired somatic genetic alterations. The most clinically relevant gene mutations include internal tandem ...
Sleep Quality, Duration and Breast Cancer Tumor Aggressiveness
Background: Epidemiological studies have reported that poor sleep quality and short sleep duration may increase breast cancer risk. However, whether sleep is associated with breast cancer tumor aggressiveness, particularly ...
The inpatient rehabilitation experience of patients with cancer
Objective : The objective of this dissertation was to describe the types of cancer patients who are referred for inpatient rehabilitation services and to examine the association between risk factors for rehabilitation ...
Prostate-specific antitumor effects of natural compounds: Isoliquiritigenin and alternol
Prostate cancer is the most commonly diagnosed form of cancer among men in the United States. It is second only to lung cancer as the leading cause of cancer-related deaths in males. The lethality of prostate cancer can ...
The effect of group counseling on the quality of life of patients and survivors of pediatric cancer and brain tumors
The purpose of this study was to examine the effect of group counseling on patients and survivors' of pediatric cancer and brain tumors perceptions of quality of life. There were five participants between the ages of 11 ...
P53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of tandem and interspersed repeats
Inactivation or loss of p53 is associated with increased cell sensitivity to the DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-dC). To identify the factors that trigger apoptotic response under these conditions, ...
Glycan Signature Changes in Stem Cell Differentiation and Cancer
Glycosyltransferase (glycoT) enzymes mediate the transfer of monosaccharide from nucleotide-sugars to carbohydrate, lipid and protein based acceptors leading to formation of glycans. The regulation of the glycan structures ...