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The role of CaMKK2 in prostate cancer progression
The androgen receptor (AR) plays a critical role in prostate cancer (PC) progression; however, the molecular mechanisms by which the AR regulates cell proliferation in androgen-dependent and castration-resistant PC (CRPC) ...
The role of SSeCKS/AKAP12 in regulating chemotaxis and metastasis
Metastasis, especially prostate cancer metastasis is a leading cause of death for men in the US. However, little is known regarding the genes and pathways that regulate this metastatic process, and moreover, it is unclear ...
The roles of the E26 transcription family member, SAM pointed domain-containing ETS transcription factor (SPDEF), in early stage prostate cancer and the development of castration recurrent disease
One of the greatest problems in prostate cancer management today is accurate identification of patients who require treatment for aggressive disease versus those with indolent disease who are suitable for observational ...