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Metabolic engineering of Escherichia coli and Saccharomyces cerevisiae to mutasynthesize natural phenylpropanoids and novel analogs
The current dissertation investigated the biosynthesis of natural and unnatural flavonoids using Escherichia coli and Saccharomyces cerevisiae. Flavonoids are a diverse group of secondary metabolites found ubiquitously in ...
Recycling acetate for improving flavanones production from Escherichia coli
Acetate is a toxic by-product of glucose metabolism in Escherichia coli. In the present work, endogenous metabolic networks of E. coli were re-designed to improve the autonomous recycling of acetate into acetyl-CoA. In ...
Robust microbial fabrication of plant pharmaceuticals: Complexities and solutions
Abstract not available.
Analysis of TGF-mediated dynamics in a system of many coupled nephrons
Previously, Pitman et al. (2002) derived an integral model of the tubuloglomerular feedback system. This integral model (also known as reduced model) describes the fluid flow up the thick ascending limb of a single, ...