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A study comparing the effects of continuous and cyclic oral contraceptive treatments on mammary gland microenvironment and tumor progression in BALB/c mice using the 4T1 transplantation model
Cyclic oral contraceptives (OC), although effective at preventing uterine and ovarian cancers, increase breast cancer risk. However, the effects of extended use (continuous) OC on breast cancer risk are unknown. We hypothesize ...
Breast epithelial morphogenesis: The role of annexins and primary cilia
Models of three dimensional (3D) mammary acinar morphogenesis are extensively used to study oncogenic transformation of breast epithelial cells. Using these models, factors and mechanisms that lead to aberrant 3D acinar ...