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The design and synthesis of chalcogenoxanthylium dyes for use as photosensitizers in photodynamic therapy (PDT) and photodynamic antimicrobial chemotherapy (PACT)
Photodynamic therapy (PDT) is an FDA-approved treatment of various cancers in the United States. Photodynamic antimicrobial chemotherapy (PACT) is a technique that is now being reinvestigated as a cleansing technique for ...
Syntheses of core-modified porphyrins, and their application to photodynamic therapy as sensitizers and halogenation reaction as catalysts
The research described in this thesis consists of five chapters. Chapter 1 describes syntheses of novel 21,23-dithia-porphyrins including their water soluble forms prepared for Photodynamic therapy (PDT) as sensitizers. ...
A comparative study of photosensitizers with and without carbohydrate moieties
Many potentially useful photosensitizers for the photodynamic therapy (PDT) of malignancies have poor tumor selectivity. We hypothesized that certain carbohydrates on conjugating with photosensitizers at the optimal position ...