Now showing items 1-10 of 40
Biophysical effects of dimyristoylphosphatidylserine on electroporation-induced skin transport regions
DMPS is known to enhance the transdermal transport of small polar solutes by electroporation significantly. Understanding the modus operandi of this enhancement is essential for the further improvement and development of ...
Remote sensing and hydrological modeling of burn scars
This study examined the potential usefulness of combining remote sensing data with hydrologic models and mapping tools available from Geographic Information Systems (GIS), to evaluate the effects of wildfire. Four subprojects ...
High yields of natural products in recombinant microorganisms using regulatory factors
Control of genetic expression, which is traditionally considered as protein's job, can also be achieved by small mRNA sequences located in 5'-UTR of any gene widely recognized as 'riboswitches'. These riboswitches control ...
Theoretical and experimental investigation of gap junctional conductance and permeability
Gap junctions are intercellular pores providing the primary means for direct exchange between cells, of ions and metabolites up to molecular weights of about 1000. They are essential for normal physiological function and ...
Endothelial cell layer subjected to flow mimicking the apex of an arterial bifurcation
Endothelial cell response to shear stress and shear stress gradients is widely accepted as a mediator of vascular pathology, including intracranial aneurysms. To this point, most in vitro research on endothelial cells ...
Blood flow measurement from digital angiography
Computational fluid dynamic (CFD) simulations are emerging as a promising tool for diagnosis and treatment planning of vascular diseases such as intracranial aneurysms. In addition to the three-dimensional luminal geometry, ...
Development and evaluation of a new high-sensitivity, region-of-interest, x-ray imaging system for neuro-interventional applications
Neurovascular image-guided interventional (IGI) procedures require very high resolution (3 to 10 lp/mm), large dynamic range, and real-time imaging capability for visualization and navigation of endovascular devices during ...
Robust microbial fabrication of plant pharmaceuticals: Complexities and solutions
Abstract not available.
Metabolic engineering of Escherichia coli and Saccharomyces cerevisiae to mutasynthesize natural phenylpropanoids and novel analogs
The current dissertation investigated the biosynthesis of natural and unnatural flavonoids using Escherichia coli and Saccharomyces cerevisiae. Flavonoids are a diverse group of secondary metabolites found ubiquitously in ...
Recycling acetate for improving flavanones production from Escherichia coli
Acetate is a toxic by-product of glucose metabolism in Escherichia coli. In the present work, endogenous metabolic networks of E. coli were re-designed to improve the autonomous recycling of acetate into acetyl-CoA. In ...