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Improving the efficacy and selectivity of photodynamic therapy (PDT): Preclinical evaluation of a novel combination strategy for cancer
Clinical application of photodynamic therapy (PDT) is limited by treatment failures that lead to tumor recurrences in patients. Based on previous observations that administration of tumor necrosis factor-alpha (TNF-α) ...
A comparative study of photosensitizers with and without carbohydrate moieties
Many potentially useful photosensitizers for the photodynamic therapy (PDT) of malignancies have poor tumor selectivity. We hypothesized that certain carbohydrates on conjugating with photosensitizers at the optimal position ...
The effect of photodynamic therapy (PDT) on epidermal growth factor receptor and interleukin-6 cytokine signaling, and tyrosine kinase inhibitors enhance the efficacy of PDT by increasing intracellular accumulation of photosensitizers
Photodynamic therapy (PDT) is a treatment for cancer which combines the administration of a drug, known as a photosensitizer, with light. When the photosensitizer is irradiated with the light, it produces singlet oxygen ...