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Mathematical Modeling of N-Glycosylation: Model Construction and Parameter Estimation from Mass Spectra of Chinese Hamster Ovary Cell Mutants
Colossal advances in molecular cellular biology have witnessed the growth of genomics, proteomics and other "–omics" fields, built on reductionist approaches aimed at annotating a vast array of biological components, from ...
Glycopeptide probes of PSGL-1 to study site-specific glycosylation and stem cell homing function
This dissertation represents an effort to develop tools to study the glycosylation of a mucinous protein called P-selectin glycoprotein ligand-1 (PSGL-1). This protein is a key adhesion molecule in inflammation and immunity. ...