Now showing items 1-4 of 4
Effects of chronic alcohol consumption and folate supplementation on the mouse mammary gland
Chronic alcohol consumption is a strong risk factor for breast cancer development in women. One potential mechanism linking alcohol and an increased risk of breast cancer development includes the ability for alcohol to ...
Structural characterization of JAA-F11-Fab by X-ray crystallography
Thomsen Friedenreich antigen (TF-Ag), is a carbohydrate antigen found on many types of tumors, including breast, prostate, bladder and ovarian. Passive transfer of JAA-F11, a monoclonal anti-TF-Ag antibody, has been shown ...
Smad3 mediates TGF-beta induced apoptosis through the control of survivin expression in human breast cancer cells
Transforming growth factor-β (TGF-β) pathway initiates signaling by assembling receptor complexes that activate Smad transcription factors. TGF-β plays a key role in cell proliferation, differentiation and apoptosis. The ...
Immunohistochemistry of carcinomas using monoclonal antibody, JAA-F11
Thomsen Friedenreich antigen (TF-Ag) is a carbohydrate antigen that is exposed on various carcinomas including those of the breast, colon, bladder and prostate . The ubiquitous nature of this antigen indicates that it ...