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Influence of the ligand binding domain heterodimer interface on NMDA receptor kinetics
Glutamatergic neurotransmission is the major contributor to excitatory synaptic communication in the mammalian brain. Activation of post-synaptic ionotropic glutamate receptors (iGluRs) causes an inward flux of positively ...
Contributions of amino-terminal domains to NMDA receptor functions
Glutamate is the major excitatory neurotransmitter in mammalian brain, and it controls excitatory synaptic transmission by binding to post-synaptic ion channels like NMDA receptors. NMDA receptor activity is important for ...