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Improving the efficacy and selectivity of photodynamic therapy (PDT): Preclinical evaluation of a novel combination strategy for cancer
Clinical application of photodynamic therapy (PDT) is limited by treatment failures that lead to tumor recurrences in patients. Based on previous observations that administration of tumor necrosis factor-alpha (TNF-α) ...
Optimization of tumor-imaging and therapeutic potential of near-infrared multifunctional agents, and targeted polyacrylamide theranostic nanoplatforms
The goal of this work was to modify the structural parameters of porphyrin-based agents to optimize their imaging and/or therapeutic potential. In order to achieve our goal, certain chlorins and bacteriochlorins were ...