Now showing items 11-20 of 137
Biophysical effects of dimyristoylphosphatidylserine on electroporation-induced skin transport regions
DMPS is known to enhance the transdermal transport of small polar solutes by electroporation significantly. Understanding the modus operandi of this enhancement is essential for the further improvement and development of ...
System-level modeling and analysis of biological reaction networks in signal transduction and glycosylation
Novel high-throughput genomic and proteomic tools are allowing the integration of information from a range of biological assays into a single conceptual framework. This framework is often described as a network of biochemical ...
Computational fluid dynamic studies of endovascular stents for treating cerebral aneurysms
Endovascular stents provide a potentially viable treatment paradigm for cerebral aneurysms by modifying their hemodynamics. To understand how different endovascular stent designs and number of stents used can differentially ...
Using molecular simulation to explore protein and colloidal phase behavior in bulk, confinement, and mixtures
Because of the ubiquity of colloidal solutions in everyday industrial applications such as papermaking and coatings there is a need to be able to efficiently design and manufacture these substances. A related issue concerns ...
Structure-property relationships in associating polymer solutions
Abstract not available.
Constructing microbial production platform for the biosynthesis of natural drug candidates-flavonoids
The current dissertation investigated the construction of production platforms for the synthesis of flavonoids in both prokaryotic host E. coli and eukaryotic host yeast S. cerevisiae. The total flavonoid biosynthetic ...
Resource shed delineation in Lake Erie
Many of the major ecological issues concerning Lake Erie, which include harmful algal blooms, spread of invasive species and toxin distribution, involve spatially explicit phenomena. In order to control these phenomena, a ...
The effect of operational parameters on the fate of tetracycline resistant bacteria in biological wastewater treatment plants
The main focus of this research is to study the fate of antibiotic resistant organisms in biological treatment processes as a function of operation and antibiotic presence. Data generated as a part of this study are expected ...
Evaluation of surface-activity-enhanced disinfectants and solutions in fiberglass-filled narrow lumens
The objective of this research was to examine whether modulation of the surface tensions of current or prospective cleaning and disinfecting solutions to lower values, could diminish the risks of secondary infection from ...
Leukocyte selectin and integrin dependent adhesion under fluid flow
Cell rolling and adhesion are important features that regulate leukocyte trafficking in human vasculature. Various adhesion molecules belonging to the selectin, integrin and immunoglobulin gene superfamilies act in synergy ...